Analgesic nephropathy
نویسندگان
چکیده
منابع مشابه
Analgesic nephropathy.
Many questions about analgesic nephropathy (AN) lack clear-cut answers. We present available evidence for and against proposed answers to many of these questions. These include: (1) Is acetaminophen (AC) nephrotoxic when taken as the sole analgesic? (2) Is the combination of acetylsalicylic acid (ASA) and AC more nephrotoxic than AC taken alone, and if so, why? (3) What are the minimum doses an...
متن کاملAspirin and analgesic nephropathy.
Renal function was studied in 17 patients with rheumatoid arthritis who had each consumed between 5 and 20 kg of aspirin. After an interval of two years 14 of these patients-seven of whom had consumed a further mean of 2 kg of aspirin-had their renal function retested. No relation was found between total dose, rate, or duration of ingestion and any aspect of renal function that was studied. All...
متن کاملAnalgesic nephropathy and papillary necrosis.
IT SEEMS likely from human and animal studies (Kincaid-Smith, 1967; Abrahams & Levin, 1967; Kincaid-Smith, Saker & McKenzie, 1968) that kidney damage resulting from a high analgesic intake in man and in animals can be explained on the basis of papillary necrosis followed by subsequent atrophy of adjacent cortical tissue. This concept makes it much easier to understand the possible mechanisms wh...
متن کاملUreteric stricture with analgesic nephropathy.
Three patients with analgesic nephropathy are reported who, in addition to the accepted features of this syndrome, had dilatation of one or both upper urinary tracts due to ureteric or periureteric fibrosis without intraluminal obstruction. We attribute this lesion to analgesic abuse and suggest that any patient with unexplained ureteric fibrosis should be questioned about analgesic consumption...
متن کاملNon-phenacetin analgesics and analgesic nephropathy
Background. A recent large-scale case-control study on analgesic nephropathy (SAN) [1] found no increased risk of end-stage renal disease (ESRD) in users of combined or single formulations of phenacetin-free analgesics. In a subgroup of 22 high users, however, a dose-dependent increased risk was found, which raised the question if these patients presented or not with analgesic nephropathy (AN)....
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ژورنال
عنوان ژورنال: Kidney International
سال: 2007
ISSN: 0085-2538
DOI: 10.1038/sj.ki.5002251